Molecular Characterization of Autophagic Responses

Molecular Characterization of Autophagic Responses

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Molecular Characterization of Autophagic Responses, Part B presents a collection of methods for the qualitative and quantitative evaluation of virtually all the morphological, biochemical, and functional manifestations of autophagy, in vitro, ex vivo and in vivo, in organisms as distant as yeast and man. Autophagy is an evolutionarily conserved mechanism for the lysosomal degradation of superfluous or dangerous cytoplasmic entities, and plays a critical role in the preservation of cellular and organismal homeostasis. Monitoring the biochemical processes that accompany autophagy is fundamental for understanding whether autophagic responses are efficient or dysfunctional. Offers a detailed overview of the protocols used to study autophagy and various aspects of autophagic responses Written in an accessible style by renowned experts in the fieldIn B. Andrews, C. Boone, T. N. Davis, aamp; S. Fields (Eds.), Budding yeast: A laboratory manual (pp. ... in the Biomedical and Life Sciences, 951a€“952, 119a€“ 128. http://dx.doi.org/10.1016/j.jchromb.2014.01.011. Kohlwein, S. D. (2010). Triacylglycerol homeostasis: Insights from yeast. Journal of Biological Chemistry, 285, 15663a€“15667. http://dx.doi.org/10.1074/jbc.R110.118356. Kohlwein, S. D., Veenhuis, M., anbsp;...


Title:Molecular Characterization of Autophagic Responses
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Publisher:Academic Press - 2017-02-22
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